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Ligand · DUC

DUC · Dihydropyrimidine-2,4(1H,3H)-dione

DUC, Dihydropyrimidine-2,4(1H,3H)-dione (C4 H6 N2 O2, 114.1 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
DUC
Formula
C4 H6 N2 O2
Class
ligand
Structures
6
PDB entries
3

Binding sites

DUC in 6 structures; the first of them:

  • 1UAQ · The crystal structure of yeast cytosine deaminase · DUC A300 · binds ILE33, ASN51, HIS62, GLY63, GLU64, LEU88, SER89, PRO90 and 6 more
  • 2FVK · Crystal structure of dihydropyrimidinase from Saccharomyces kluyveri in complex with the… · DUC A604 · binds HIS62, HIS64, LEU72, KCX167, TYR172, HIS199, HIS255, CYS330 and 5 more
  • 4XK4 · E. coli transcriptional regulator RUTR with dihydrouracil · DUC A300 · binds LEU74, TRP77, LEU78, LYS101, PHE115, LEU134, TRP167, GLN171 and 2 more
  • 1UAQ · The crystal structure of yeast cytosine deaminase · DUC A300 · binds ILE33, ASN51, HIS62, GLY63, GLU64, LEU88, SER89, PRO90 and 6 more
  • 2FVK · Crystal structure of dihydropyrimidinase from saccharomyces kluyveri in complex with the… · DUC A604 · binds HIS62, HIS64, LEU72, KCX167, TYR172, HIS199, HIS255, CYS330 and 5 more
  • 4XK4 · E. COLI transcriptional regulator rutr with dihydrouracil · DUC A300 · binds LEU74, TRP77, LEU78, LYS101, PHE115, LEU134, TRP167, GLN171 and 2 more

Residues it binds most

HIS 12, LEU 20, CYS 12, PHE 16, TRP 12, GLN 8, ASN 12, ASP 12, GLY 12, SER 12 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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