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Ligand · DTF

DTF · 4-[(10S,14S,18S)-18-(2-amino-2-oxoethyl)-14-(1-naphthylmethyl)-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl]benzylphosphonic acid

DTF, 4-[(10S,14S,18S)-18-(2-amino-2-oxoethyl)-14-(1-naphthylmethyl)-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl]benzylphosphonic acid (C37 H45 N4 O7 P, 688.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component
DTF
Formula
C37 H45 N4 O7 P
Class
ligand
Structures
2
PDB entries
1

Binding sites

DTF in 2 structures; the first of them:

  • 1X0N · NMR structure of growth factor receptor binding protein SH2 domain complexed with the… · DTF A174 · binds ARG67, ARG86, SER96, GLN106, HIS107, PHE108, LYS109, LEU111 and 2 more
  • 1X0N · NMR structure of growth factor receptor binding protein SH2 domain complexed with the… · DTF A174 · binds ARG67, ARG86, SER96, GLN106, HIS107, PHE108, LYS109, LEU111 and 2 more

Residues it binds most

ARG 2, LEU 2, GLN 2, HIS 2, LYS 2, PHE 2, SER 2, TRP 2 (residue and the binding sites it lines).

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