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Ligand · DT7

DT7 · 6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide

DT7, 6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide (C11 H16 N2 O4 S, 272.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
DT7
Formula
C11 H16 N2 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

DT7 in 2 structures; the first of them:

  • 3IGP · Structure of inhibitor binding to Carbonic Anhydrase II · DT7 A263 · binds GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, PHE131, VAL143 and 7 more
  • 3IGP · Structure of inhibitor binding to carbonic anhydrase II · DT7 A263 · binds GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, PHE131, VAL143 and 7 more

Residues it binds most

HIS 4, TRP 4, PHE 4, PRO 2, THR 2, VAL 2, ASN 2, ASP 2, GLN 2, GLU 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • GOL · Glycerol

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