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Ligand · DT4

DT4 · 4-({5-[(4-aminocyclohexyl)amino][1,2,4]triazolo[1,5-a]pyrimidin-7-yl}amino)benzenesulfonamide

DT4, 4-({5-[(4-aminocyclohexyl)amino][1,2,4]triazolo[1,5-a]pyrimidin-7-yl}amino)benzenesulfonamide (C17 H22 N8 O2 S, 402.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
DT4
Formula
C17 H22 N8 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

DT4 in 2 structures; the first of them:

  • 2C6L · Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor · DT4 A1299 · binds ILE10, GLU12, GLY13, VAL18, ALA31, LYS33, VAL64, PHE80 and 12 more
  • 2C6L · Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor · DT4 A1299 · binds ILE10, GLU12, GLY13, VAL18, ALA31, LYS33, VAL64, PHE80 and 12 more

Residues it binds most

LYS 2, ASP 2, GLN 2, GLU 2, LEU 2, PHE 2, VAL 2, ALA 2, ASN 2, GLY 2 (residue and the binding sites it lines).

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