DOQ · (2S,3S,4S)-2-carboxy-4-[(1Z,3E,5R)-5-carboxy-1-methyl-1,3-hexadienyl]-3-pyrrolidineacetic acid

Binding sites

DOQ in 8 structures; the first of them:

• 1YAE · Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with… · DOQ A901 · binds GLU440, LYS487, TYR488, GLY489, PRO516, LEU517, ALA518, ARG523 and 10 more
• 2PBW · Crystal Structure of the Ligand-Binding Core of iGluR5 in Complex with the Partial… · DOQ A401 · binds GLU13, GLY59, LYS60, TYR61, GLY62, PRO88, LEU89, THR90 and 10 more
• 8GC2 · Domoate-bound GluK2 kainate receptor in partially-open conformation 1 · DOQ A1003 · binds GLU440, GLU441, LYS487, TYR488, GLY489, ALA490, PRO516, LEU517 and 12 more
• 8GC3 · Domote-bound GluK2 kainate receptors in partially-open conformation 2 · DOQ A1002 · binds GLU440, GLY486, LYS487, TYR488, GLY489, PRO516, LEU517, ALA518 and 11 more
• 8GC4 · Domoate-bound GluK2 kainate receptor in partially-open conformation 3 · DOQ A1002 · binds LYS487, TYR488, GLY489, ALA490, PRO516, LEU517, ALA518, ARG523 and 9 more
• 8GC5 · Domoate-bound GluK2 kainate receptors in non-active conformation · DOQ A1002 · binds GLU440, LYS487, TYR488, GLY489, ALA490, PRO516, LEU517, ALA518 and 10 more
• 1YAE · Structure of the kainate receptor subunit GLUR6 agonist binding domain complexed with… · DOQ A1103 · binds GLU440, LYS487, TYR488, GLY489, PRO516, LEU517, ALA518, ARG523 and 10 more
• 2PBW · Crystal structure of the ligand-binding core of IGLUR5 in complex with the partial… · DOQ A401 · binds GLU13, GLY59, LYS60, TYR61, GLY62, PRO88, LEU89, THR90 and 10 more

Residues it binds most

GLU 31, GLY 31, ALA 27, TYR 31, LYS 31, LEU 29, ARG 28, THR 28, VAL 31, ASP 29 (residue and the binding sites it lines).

Found with

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
• BMA · beta-D-mannopyranose
• MAN · alpha-D-mannopyranose
• FUC · alpha-L-fucopyranose