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Ligand · DIZ

DIZ · (4-chlorophenyl)[3-(4-chlorophenyl)-7-iodo-2,5-dioxo-1,2,3,5-tetrahydro-4H-1,4-benzodiazepin-4-yl]acetic acid

DIZ, (4-chlorophenyl)[3-(4-chlorophenyl)-7-iodo-2,5-dioxo-1,2,3,5-tetrahydro-4H-1,4-benzodiazepin-4-yl]acetic acid (C23 H15 Cl2 I N2 O4, 581.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
DIZ
Formula
C23 H15 Cl2 I N2 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

DIZ in 2 structures; the first of them:

  • 1T4E · Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor · DIZ A112 · binds GLY16, SER17, LEU54, LEU57, GLY58, ILE61, MET62, TYR67 and 7 more
  • 1T4E · Structure of human MDM2 in complex with a benzodiazepine inhibitor · DIZ A112 · binds GLY16, SER17, LEU54, LEU57, GLY58, ILE61, MET62, TYR67 and 7 more

Residues it binds most

GLY 4, ILE 4, LEU 4, PHE 4, TYR 4, VAL 4, GLN 4, HIS 4, MET 4, SER 4 (residue and the binding sites it lines).

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