GL1X · GenesisL1 explorer

Ligand · DFS

DFS · 2,6-difluoro-N-(1H-imidazo[4,5-b]pyridin-6-yl)-3-[(propylsulfonyl)amino]benzamide

DFS, 2,6-difluoro-N-(1H-imidazo[4,5-b]pyridin-6-yl)-3-[(propylsulfonyl)amino]benzamide (C16 H15 F2 N5 O3 S, 395.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
DFS
Formula
C16 H15 F2 N5 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

DFS in 2 structures; the first of them:

  • 4MBJ · Human B-Raf Kinase Domain in Complex with an Imidazopyridine-based Inhibitor · DFS A801 · binds ILE463, PHE468, VAL471, ALA481, LYS483, LEU505, LEU514, ILE527 and 9 more
  • 4MBJ · Human B-RAF kinase domain in complex with an imidazopyridine-based inhibitor · DFS A801 · binds ILE463, PHE468, VAL471, ALA481, LYS483, LEU505, LEU514, ILE527 and 9 more

Residues it binds most

ILE 4, LEU 4, GLY 4, PHE 4, VAL 4, ALA 4, ASP 4, CYS 4, GLN 4, LYS 4 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.