Ligand · DFQ
DFQ · (2E)-3-{6-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]quinolin-3-yl}-N-methylprop-2-enamide
DFQ, (2E)-3-{6-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]quinolin-3-yl}-N-methylprop-2-enamide (C21 H17 Cl2 F N2 O2, 419.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…
- Component
- DFQ
- Formula
- C21 H17 Cl2 F N2 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
DFQ in 2 structures; the first of them:
- 3A4P · human c-MET kinase domain complexed with 6-benzyloxyquinoline inhibitor · DFQ A1362 · binds ILE1084, GLY1085, VAL1092, ALA1108, LEU1140, LEU1157, PRO1158, TYR1159 and 11 more
- 3A4P · Human C-met kinase domain complexed with 6-benzyloxyquinoline inhibitor · DFQ A1362 · binds ILE1084, GLY1085, VAL1092, ALA1108, LEU1140, LEU1157, PRO1158, TYR1159 and 11 more
Residues it binds most
ALA 2, GLY 2, LEU 2, MET 2, TYR 2, ARG 2, ASN 2, ASP 2, HIS 2, ILE 2 (residue and the binding sites it lines).
Found with
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