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Ligand · DFN

DFN · 3-[3-(2,3-dihydroxy-propylamino)-phenyl]-4-(5-fluoro-1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione

DFN, 3-[3-(2,3-dihydroxy-propylamino)-phenyl]-4-(5-fluoro-1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione (C22 H20 F N3 O4, 409.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
DFN
Formula
C22 H20 F N3 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

DFN in 2 structures; the first of them:

  • 1R0E · Glycogen synthase kinase-3 beta in complex with 3-indolyl-4-arylmaleimide inhibitor · DFN A702 · binds ILE62, GLY63, ASN64, PHE67, VAL70, ALA83, LYS85, VAL110 and 11 more
  • 1R0E · Glycogen synthase kinase-3 beta in complex with 3-indolyl-4- arylmaleimide inhibitor · DFN A702 · binds ILE62, GLY63, ASN64, PHE67, VAL70, ALA83, LYS85, VAL110 and 11 more

Residues it binds most

VAL 4, ASN 4, ASP 4, LEU 4, ALA 4, CYS 4, GLN 4, GLY 4, ILE 4, LYS 4 (residue and the binding sites it lines).

Found with

  • FLC · Citrate anion

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