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Ligand · DF6

DF6 · N-({4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}carbamothioyl)-2-phenylacetamide

DF6, N-({4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}carbamothioyl)-2-phenylacetamide (C26 H23 N3 O4 S, 473.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
DF6
Formula
C26 H23 N3 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

DF6 in 2 structures; the first of them:

  • 3VW8 · Crystal structure of human c-Met kinase domain with its inhibitor · DF6 A1401 · binds ILE1084, VAL1092, ALA1108, LYS1110, GLU1127, GLY1128, ILE1130, MET1131 and 18 more
  • 3VW8 · Crystal structure of human C-met kinase domain with its inhibitor · DF6 A1401 · binds ILE1084, VAL1092, ALA1108, LYS1110, GLU1127, GLY1128, ILE1130, MET1131 and 18 more

Residues it binds most

VAL 2, LEU 2, MET 2, PHE 2, ALA 2, GLY 2, ILE 2, LYS 2, ASP 2, GLU 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

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