Ligand · D7D
D7D · N-{cis-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl) amino]cyclobutyl}propane-1-sulfonamide
D7D, N-{cis-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl) amino]cyclobutyl}propane-1-sulfonamide (C14 H21 N5 O2 S, 323.4 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its residues…
- Component
- D7D
- Formula
- C14 H21 N5 O2 S
- Class
- ligand
- Structures
- 3
- PDB entries
- 2
Binding sites
D7D in 3 structures; the first of them:
- 6BBV · Crystal Structure of JAK2 in complex with compound 25 · D7D A1201 · binds LEU855, GLY856, LYS857, GLY858, GLY861, VAL863, ALA880, VAL911 and 9 more
- 6BBU · Crystal structure of JAK1 in complex with compound 25 · D7D A4000 · binds LEU881, GLY882, GLU883, GLY884, ALA906, LYS908, VAL938, MET956 and 9 more
- 6BBV · Crystal structure of JAK2 in complex with compound 25 · D7D A1201 · binds LEU855, GLY856, LYS857, GLY858, GLY861, VAL863, ALA880, VAL911 and 9 more
Residues it binds most
GLY 3, LEU 3, GLU 3, VAL 3, ALA 3, ARG 3, ASN 3, ASP 3, LYS 3, MET 3 (residue and the binding sites it lines).
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