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Ligand · D73

D73 · [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-2,3,4-trihydroxy-5-[(4aS)-4a-[(1S,3E)-3-imino-1-phenylbutyl]-7,8-dimethyl-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]pentyl dihydrogen diphosphate

D73, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-2,3,4-trihydroxy-5-[(4aS)-4a-[(1S,3E)-3-imino-1-phenylbutyl]-7,8-dimethyl-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]pentyl…

Component
D73
Formula
C37 H46 N10 O15 P2
Class
ligand
Structures
2
PDB entries
1

Binding sites

D73 in 2 structures; the first of them:

  • 4UVA · LSD1(KDM1A)-CoREST in complex with 1-Methyl-Tranylcypromine (1R,2S) · D73 A900 · binds ILE284, GLY285, SER286, GLY287, VAL288, SER289, GLY290, LEU307 and 37 more
  • 4UVA · LSD1(KDM1A)-corest in complex with 1-methyl-tranylcypromine (1R,2S) · D73 A900 · binds ILE284, GLY285, SER286, GLY287, VAL288, SER289, GLY290, LEU307 and 37 more

Residues it binds most

GLY 2, VAL 2, ALA 2, LEU 2, THR 2, SER 2, ARG 2, GLU 2, TRP 2, TYR 2 (residue and the binding sites it lines).

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