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Ligand · D3T

D3T · 2',3'-dideoxy-thymidine-5'-triphosphate

D3T, 2',3'-dideoxy-thymidine-5'-triphosphate (C10 H17 N2 O13 P3, 466.2 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
D3T
Formula
C10 H17 N2 O13 P3
Class
ligand
Structures
5
PDB entries
4

Binding sites

D3T in 5 structures; the first of them:

  • 7KC0 · Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a… · D3T A1102 · binds DC25, DA0, DG1, ASP608, PHE609, ASN610, SER611, LEU612 and 9 more
  • 8V5R · Active conformation of DNA polymerase gamma bound to DNA · D3T A1302 · binds ARG853, ASP890, VAL891, ASP892, SER893, GLN894, GLU895, LYS925 and 10 more
  • 8WPE · Structure of monkeypox virus polymerase complex F8-A22-E4-H5 (tag-free A22) with… · D3T A2001 · binds ASP549, TYR550, ASN551, SER552, LEU553, TYR554, ARG634, LYS638 and 10 more
  • 8WPF · Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exogenous DNA bearing… · D3T A2001 · binds ASP549, TYR550, ASN551, SER552, LEU553, TYR554, ARG634, LYS638 and 9 more
  • 7KC0 · Structure of the saccharomyces cerevisiae replicative polymerase delta in complex with a… · D3T A1102 · binds DC25, DA0, DG1, ASP608, PHE609, ASN610, SER611, LEU612 and 7 more

Residues it binds most

ASP 5, TYR 5, LYS 5, ASN 4, ARG 5, DA 5, ILE 5, SER 5, DC 4, DG 4 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • SF4 · Iron/sulfur cluster
  • ZN · Zinc ion

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