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Ligand · D37

D37 · N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide

D37, N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide (C18 H23 N7 O2 S, 401.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
D37
Formula
C18 H23 N7 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

D37 in 2 structures; the first of them:

  • 3R22 · Design, synthesis, and biological evaluation of pyrazolopyridine-sulfonamides as potent… · D37 A1 · binds ARG137, LEU139, GLY140, LYS141, VAL147, ALA160, LEU194, LEU210 and 9 more
  • 3R22 · Design, synthesis, and biological evaluation of pyrazolopyridine- sulfonamides as potent… · D37 A1 · binds ARG137, LEU139, GLY140, LYS141, VAL147, ALA160, LEU194, LEU210 and 9 more

Residues it binds most

LEU 2, ALA 2, ARG 2, GLU 2, GLY 2, LYS 2, PRO 2, THR 2, TYR 2, VAL 2 (residue and the binding sites it lines).

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