Ligand · D1R
D1R · Nalpha-[(4-methylpiperazin-1-yl)carbonyl]-N-{(1S)-3-phenyl-1-[2-(phenylsulfonyl)ethyl]propyl}-L-phenylalaninamide
D1R, Nalpha-[(4-methylpiperazin-1-yl)carbonyl]-N-{(1S)-3-phenyl-1-[2-(phenylsulfonyl)ethyl]propyl}-L-phenylalaninamide (C32 H40 N4 O4 S, 576.8 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (3 PDB entries). Every binding…
- Component
- D1R
- Formula
- C32 H40 N4 O4 S
- Class
- ligand
- Structures
- 5
- PDB entries
- 3
Binding sites
D1R in 5 structures; the first of them:
- 2OZ2 · Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (K11777) · D1R A301 · binds GLN19, GLY23, CYS25, TRP26, SER61, CYS63, SER64, GLY65 and 14 more
- 2P7U · The crystal structure of rhodesain, the major cysteine protease of T. brucei rhodesiense… · D1R A300 · binds GLN19, CYS22, GLY23, CYS25, TRP26, PHE61, CYS63, GLY64 and 11 more
- 8QKB · Crystal structure of human cathepsin L in complex with the vinyl sulfone inhibitor K777 · D1R A301 · binds GLN19, GLY23, SER24, CYS25, TRP26, GLY61, GLU63, CYS65 and 14 more
- 2OZ2 · Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (K11777) · D1R A301 · binds GLN19, GLY23, CYS25, TRP26, SER61, CYS63, SER64, GLY65 and 14 more
- 2P7U · The crystal structure of rhodesain, the major cysteine protease of T. brucei rhodesiense… · D1R A300 · binds GLN19, CYS22, GLY23, CYS25, TRP26, PHE61, CYS63, GLY64 and 11 more
Residues it binds most
GLY 10, ALA 10, CYS 10, MET 10, TRP 10, LEU 10, SER 8, ASP 10, GLN 10, HIS 10 (residue and the binding sites it lines).
Found with
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