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Ligand · CXR

CXR · Cyclic adenosine diphosphate-ribose

CXR, Cyclic adenosine diphosphate-ribose (C15 H21 N5 O13 P2, 541.3 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
CXR
Formula
C15 H21 N5 O13 P2
Class
ligand
Structures
8
PDB entries
4

Binding sites

CXR in 8 structures; the first of them:

  • 2O3Q · Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by… · CXR A301 · binds TRP125, ARG127, LYS129, LEU145, GLU146, ASP155, ASP156, LEU157 and 5 more
  • 2O3R · Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by… · CXR A301 · binds TRP125, ARG127, LYS129, LEU145, GLU146, ASP155, ASP156, LEU157 and 6 more
  • 2O3S · Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by… · CXR A301 · binds TRP125, ARG127, LYS129, LEU145, GLU146, ASP155, ASP156, LEU157 and 5 more
  • 3ZWM · Crystal structure of ADP ribosyl cyclase complexed with substrate NAD and product cADPR · CXR F303 · binds PHE76, TRP77, SER78, GLY79, LEU97, GLU98, PHE128, TRP140 and 7 more
  • 2O3Q · Structural basis for formation and hydrolysis of calcium messenger cyclic ADP-ribose by… · CXR A301 · binds TRP125, ARG127, LYS129, LEU145, GLU146, ASP155, ASP156, LEU157 and 5 more
  • 2O3R · Structural basis for formation and hydrolysis of calcium messenger cyclic ADP-ribose by… · CXR A301 · binds TRP125, ARG127, LYS129, LEU145, GLU146, ASP155, ASP156, LEU157 and 6 more
  • 2O3S · Structural basis for formation and hydrolysis of calcium messenger cyclic ADP-ribose by… · CXR A301 · binds TRP125, ARG127, LYS129, LEU145, GLU146, ASP155, ASP156, LEU157 and 5 more
  • 3ZWM · Crystal structure of ADP ribosyl cyclase complexed with substrate NAD and product cadpr · CXR F303 · binds PHE76, TRP77, SER78, GLY79, LEU97, GLU98, PHE128, TRP140 and 7 more

Residues it binds most

SER 16, TRP 16, LEU 16, ASP 12, GLU 16, THR 12, PHE 4, ARG 12, LYS 12, VAL 12 (residue and the binding sites it lines).

Found with

  • NAD · Nicotinamide-adenine-dinucleotide

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