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Ligand · CU8

CU8 · 7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

CU8, 7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (C14 H12 N4 O, 252.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
CU8
Formula
C14 H12 N4 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

CU8 in 2 structures; the first of them:

  • 5WYX · Crystal structure of human TLR8 in complex with CU-CPT8m · CU8 A916 · binds PHE494, PHE495, ALA518, GLN519, VAL520, PHE261, ASN262, PHE346 and 9 more
  • 5WYX · Crystal structure of human TLR8 in complex with cu-CPT8M · CU8 A916 · binds PHE494, PHE495, ALA518, GLN519, VAL520, PHE261, ASN262, PHE346 and 9 more

Residues it binds most

PHE 4, GLY 4, VAL 4, ILE 4, TYR 4, ALA 4, ASN 4, GLN 4, LYS 4, SER 4 (residue and the binding sites it lines).

Found with

  • BMA · beta-D-mannopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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