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Ligand · CTZ

CTZ · C2-hydroxy-coelenterazine

CTZ, C2-hydroxy-coelenterazine (C26 H21 N3 O4, 439.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
CTZ
Formula
C26 H21 N3 O4
Class
ligand
Structures
4
PDB entries
2

Binding sites

CTZ in 4 structures; the first of them:

  • 1EL4 · Structure of the calcium-regulated photoprotein obelin determined by sulfur sas · CTZ A197 · binds HIS22, MET25, PHE28, LEU29, ILE42, LYS45, ALA46, ILE50 and 17 more
  • 2HPS · Crystal structure of coelenterazine-binding protein from Renilla Muelleri · CTZ A187 · binds ARG19, MSE20, ARG22, VAL23, TYR36, ILE39, PHE61, GLN103 and 14 more
  • 1EL4 · Structure of the calcium-regulated photoprotein obelin determined by sulfur sas · CTZ A197 · binds HIS22, MET25, PHE28, LEU29, ILE42, LYS45, ALA46, ILE50 and 17 more
  • 2HPS · Crystal structure of coelenterazine-binding protein from renilla muelleri · CTZ A187 · binds ARG19, MSE20, ARG22, VAL23, TYR36, ILE39, PHE61, GLN103 and 14 more

Residues it binds most

PHE 4, ILE 4, VAL 4, TRP 2, TYR 4, LEU 4, ALA 4, ARG 2, GLY 4, HIS 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • GOL · Glycerol

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