GL1X · GenesisL1 explorer

Ligand · COG

COG · 2,4-diamino-6-[N-(2',5'-dimethoxybenzyl)-N-methylamino]quinazoline

COG, 2,4-diamino-6-[N-(2',5'-dimethoxybenzyl)-N-methylamino]quinazoline (C18 H21 N5 O2, 339.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
COG
Formula
C18 H21 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

COG in 2 structures; the first of them:

  • 1LY3 · Analysis of quinazoline and pyridopyrimidine N9-C10 reversed bridge antifolates in… · COG A307 · binds ILE10, VAL11, ALA12, SER24, LEU25, GLU32, ILE33, PHE36 and 9 more
  • 1LY3 · Analysis of quinazoline and pyridopyrimidine N9-C10 reversed bridge antifolates in… · COG A307 · binds ILE10, VAL11, ALA12, SER24, LEU25, GLU32, ILE33, PHE36 and 9 more

Residues it binds most

ILE 2, LEU 2, PHE 2, SER 2, THR 2, ALA 2, GLU 2, PRO 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.