CNI · 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile

Binding sites

CNI in 8 structures; the first of them:

• 3B7D · Crystal structure of the GLUR2 ligand binding core (HS1S2J) in complex with CNQX at 2.5 A… · CNI A262 · binds GLU13, TYR16, TYR61, PRO89, LEU90, THR91, ARG96, SER142 and 5 more
• 3T9U · CNQX bound to an oxidized double cysteine mutant (A452C/S652C) of the ligand binding… · CNI A400 · binds GLU13, TYR16, TYR61, PRO89, LEU90, THR91, ARG96, LEU138 and 8 more
• 3T9V · CNQX bound to a reduced double cysteine mutant (A452C/S652C) of the ligand binding domain… · CNI A400 · binds GLU13, TYR16, TYR61, PRO89, LEU90, THR91, ARG96, THR174 and 4 more
• 4F1Y · CNQX bound to the ligand binding domain of GluA3 · CNI A401 · binds GLU13, TYR16, TYR61, PRO89, LEU90, THR91, ARG96, THR174 and 4 more
• 3B7D · Crystal structure of the GLUR2 ligand binding core (HS1S2J) in complex with cnqx at 2.5 a… · CNI A262 · binds GLU13, TYR16, TYR61, PRO89, LEU90, THR91, ARG96, SER142 and 5 more
• 3T9U · Cnqx bound to an oxidized double cysteine mutant (A452C/S652C) of the ligand binding… · CNI A400 · binds GLU13, TYR16, TYR61, PRO89, LEU90, THR91, ARG96, LEU138 and 8 more
• 3T9V · Cnqx bound to a reduced double cysteine mutant (A452C/S652C) of the ligand binding domain… · CNI A400 · binds GLU13, TYR16, TYR61, PRO89, LEU90, THR91, ARG96, THR174 and 4 more
• 4F1Y · Cnqx bound to the ligand binding domain of GLUA3 · CNI A401 · binds GLU13, TYR16, TYR61, PRO89, LEU90, THR91, ARG96, THR174 and 4 more

Residues it binds most

TYR 30, THR 30, GLU 30, LEU 30, ARG 30, MET 30, PRO 30, SER 14, GLY 6 (residue and the binding sites it lines).

Found with

• ZN · Zinc ion