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Ligand · CJ6

CJ6 · N4-cyclopropyl-6-(4-methylpiperazin-1-yl)pyrimidine-2, 4-diamine

CJ6, N4-cyclopropyl-6-(4-methylpiperazin-1-yl)pyrimidine-2, 4-diamine (C12 H20 N6, 248.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
CJ6
Formula
C12 H20 N6
Class
ligand
Structures
2
PDB entries
1

Binding sites

CJ6 in 2 structures; the first of them:

  • 6JVO · Crystal structure of human MTH1 in complex with compound MI1022 · CJ6 A200 · binds THR8, LEU9, ASN33, GLY37, PHE72, PHE74, MET81, TRP117 and 4 more
  • 6JVO · Crystal structure of human MTH1 in complex with compound MI1022 · CJ6 A200 · binds THR8, LEU9, ASN33, GLY37, PHE72, PHE74, MET81, TRP117 and 4 more

Residues it binds most

PHE 4, ASP 4, TRP 4, ASN 4, GLY 4, LEU 4, THR 4, MET 2, TYR 2 (residue and the binding sites it lines).

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