GL1X · GenesisL1 explorer

Ligand · CIO

CIO · Cilomilast

CIO, Cilomilast (C20 H25 N O4, 343.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
CIO
Formula
C20 H25 N O4
Class
ligand
Structures
4
PDB entries
2

Binding sites

CIO in 4 structures; the first of them:

  • 1XLX · Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Cilomilast · CIO A101 · binds TYR233, HIS234, HIS278, GLU304, THR345, MET347, ASP392, LEU393 and 11 more
  • 1XOM · Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Cilomilast · CIO A603 · binds TYR159, HIS160, GLU230, MET273, LEU319, ASN321, TYR329, TRP332 and 8 more
  • 1XLX · Catalytic domain of human phosphodiesterase 4B in complex with cilomilast · CIO A101 · binds TYR233, HIS234, HIS278, GLU304, THR345, MET347, ASP392, LEU393 and 11 more
  • 1XOM · Catalytic domain of human phosphodiesterase 4D in complex with cilomilast · CIO A603 · binds TYR159, HIS160, GLU230, MET273, LEU319, ASN321, TYR329, TRP332 and 8 more

Residues it binds most

MET 8, PHE 8, TYR 8, HIS 8, THR 8, ASN 8, GLN 8, ILE 8, LEU 8, SER 8 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.