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Ligand · CGW

CGW · (2~{S})-2-azanyl-3-[2,4-bis(oxidanylidene)-5,7-dihydrothieno[3,4-d]pyrimidin-1-yl]propanoic acid

CGW, (2~{S})-2-azanyl-3-[2,4-bis(oxidanylidene)-5,7-dihydrothieno[3,4-d]pyrimidin-1-yl]propanoic acid (C9 H11 N3 O4 S, 257.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…

Component
CGW
Formula
C9 H11 N3 O4 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

CGW in 4 structures; the first of them:

  • 6F29 · Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with… · CGW A301 · binds GLU15, PHE18, TYR63, PRO90, LEU91, THR92, ARG97, VAL139 and 8 more
  • 6YK2 · Structure of the AMPA receptor GluA2o ligand-binding domain (S1S2J) in complex with the… · CGW A309 · binds GLU13, TYR16, TYR61, PRO89, LEU90, THR91, ARG96, LEU138 and 9 more
  • 6F29 · Crystal structure of the kainate receptor GLUK3 ligand binding domain in complex with… · CGW A301 · binds GLU15, PHE18, TYR63, PRO90, LEU91, THR92, ARG97, VAL139 and 8 more
  • 6YK2 · Structure of the AMPA receptor GLUA2O ligand-binding domain (S1S2J) in complex with the… · CGW A309 · binds GLU13, TYR16, TYR61, PRO89, LEU90, THR91, ARG96, LEU138 and 9 more

Residues it binds most

THR 4, TYR 4, GLU 4, LEU 4, ARG 4, GLY 4, MET 4, PRO 4, SER 2, ALA 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • K · Potassium ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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