GL1X · GenesisL1 explorer

Ligand · CFB

CFB · 2-chloro-9-(2-deoxy-2-fluoro-B -D-arabinofuranosyl)-9H-purin-6-amine

CFB, 2-chloro-9-(2-deoxy-2-fluoro-B -D-arabinofuranosyl)-9H-purin-6-amine (C10 H11 Cl F N5 O3, 303.7 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
CFB
Formula
C10 H11 Cl F N5 O3
Class
ligand
Structures
3
PDB entries
2

Binding sites

CFB in 3 structures; the first of them:

  • 7CWA · Crystal structure of PDE8A catalytic domain in complex with clofarabine · CFB A903 · binds TYR555, HIS556, THR668, MET670, ASP726, VAL727, ASN729, ILE744 and 4 more
  • 8PQQ · Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 E88Q… · CFB A201 · binds TYR7, ALA9, SER10, PHE14, PRO40, PHE41, ASN44, TRP54 and 10 more
  • 7CWA · Crystal structure of PDE8A catalytic domain in complex with clofarabine · CFB A903 · binds TYR555, HIS556, MET670, ASP726, VAL727, ASN729, ILE744, TYR748 and 2 more

Residues it binds most

ASP 6, PHE 6, ASN 6, VAL 6, TYR 6, GLN 6, MET 6, PRO 4, ALA 4, GLY 4 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.