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Ligand · CDK

CDK · 4-[4-(3,4-dimethyl-2-oxo-2,3-dihydro-thiazol-5-yl)-pyrimidin-2-ylamino]-N-(2-methoxy-ethyl)-benzenesulfonamide

CDK, 4-[4-(3,4-dimethyl-2-oxo-2,3-dihydro-thiazol-5-yl)-pyrimidin-2-ylamino]-N-(2-methoxy-ethyl)-benzenesulfonamide (C18 H21 N5 O4 S2, 435.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
CDK
Formula
C18 H21 N5 O4 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

CDK in 2 structures; the first of them:

  • 2XMY · Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional… · CDK A500 · binds ILE10, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81, PHE82 and 10 more
  • 2XMY · Discovery and characterisation of 2-anilino-4-(thiazol-5-yl) pyrimidine transcriptional… · CDK A500 · binds ILE10, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81, PHE82 and 10 more

Residues it binds most

ALA 2, ASP 2, GLN 2, LEU 2, LYS 2, PHE 2, VAL 2, ASN 2, GLU 2, HIS 2 (residue and the binding sites it lines).

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