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Ligand · CBO

CBO · Carbenoxolone

CBO, Carbenoxolone (C34 H50 O7, 570.8 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
CBO
Formula
C34 H50 O7
Class
ligand
Structures
3
PDB entries
3

Binding sites

CBO in 3 structures; the first of them:

  • 6WBI · Cryo-EM structure of human pannexin 1 channel with its C-terminal tail cleaved by… · CBO A401 · binds TRP74
  • 6WBL · Cryo-EM structure of human pannexin 1 channel with deletion of N- terminal helix and… · CBO E401
  • 7BYI · Structure of SHMT2 in complex with cbx · CBO B601 · binds LEU166, LEU172, ILE183, SER226, HIS254, ARG425, GLU98, TYR105 and 3 more

Residues it binds most

LEU 2, TYR 2, GLU 2, HIS 2, ILE 2, SER 2, ARG 1, PHE 1, PRO 1, TRP 1 (residue and the binding sites it lines).

Found with

  • PO4 · Phosphate ion
  • PEG · Di(hydroxyethyl)ether

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