GL1X · GenesisL1 explorer

Ligand · C7W

C7W · (3R,3aS,4R,6aR)-4-(3,3,3-trifluoropropoxy)hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[2-(methylamino)-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate

C7W, (3R,3aS,4R,6aR)-4-(3,3,3-trifluoropropoxy)hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[2-(methylamino)-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate (C32 H41 F3 N4 O9 S, 714.8 g/mol), in…

Component
C7W
Formula
C32 H41 F3 N4 O9 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

C7W in 2 structures; the first of them:

  • 5AH8 · Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease… · C7W A1101 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, GLY48, GLY49 and 19 more
  • 5AH8 · Disubstituted bis-thf moieties as new P2 ligands in non-peptidal HIV- 1 protease… · C7W A1101 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, GLY48, GLY49 and 19 more

Residues it binds most

ASP 2, GLY 2, ILE 2, VAL 2, ALA 2, LEU 2, THR 2, LYS 2, PHE 2, PRO 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.