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Ligand · C7U

C7U · (3R,3aS,4R,6aS)-4-chlorohexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[2-(methylamino)-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate

C7U, (3R,3aS,4R,6aS)-4-chlorohexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[2-(methylamino)-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate (C29 H37 Cl N4 O8 S, 637.1 g/mol), in the MolNFT…

Component
C7U
Formula
C29 H37 Cl N4 O8 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

C7U in 2 structures; the first of them:

  • 5AH6 · Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease… · C7U A1101 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, GLY48 and 19 more
  • 5AH6 · Disubstituted bis-thf moieties as new P2 ligands in non-peptidal HIV- 1 protease… · C7U A1101 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, GLY48 and 19 more

Residues it binds most

ASP 2, GLY 2, VAL 2, ILE 2, ALA 2, LEU 2, THR 2, LYS 2, PRO 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

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