GL1X · GenesisL1 explorer

Ligand · C5I

C5I · 3-oxo-3-[(3R)-3-(pyrrolo[2,3-b][1,2,3]triazolo[4,5-d]pyridin-1(6H)-yl)piperidin-1-yl]propanenitrile

C5I, 3-oxo-3-[(3R)-3-(pyrrolo[2,3-b][1,2,3]triazolo[4,5-d]pyridin-1(6H)-yl)piperidin-1-yl]propanenitrile (C15 H15 N7 O, 309.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
C5I
Formula
C15 H15 N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

C5I in 2 structures; the first of them:

  • 4I5C · The Jak1 kinase domain in complex with inhibitor · C5I A1201 · binds LEU881, GLY882, GLU883, GLY884, GLY887, LYS888, VAL889, ALA906 and 13 more
  • 4I5C · The JAK1 kinase domain in complex with inhibitor · C5I A1201 · binds LEU881, GLY882, GLU883, GLY884, GLY887, LYS888, VAL889, ALA906 and 13 more

Residues it binds most

GLY 4, LEU 4, GLU 4, LYS 4, VAL 4, ALA 4, ARG 4, ASN 4, ASP 4, MET 4 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.