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Ligand · C35

C35 · N~2~-{[1-(4-chlorophenyl)-5-methyl-1H-1,2,4-triazol-3-yl]carbonyl}-N~5~-(diaminomethylidene)-L-ornithyl-L-leucyl-L-isoleucyl-4-fluoro-L-phenylalaninamide

C35, N~2~-{[1-(4-chlorophenyl)-5-methyl-1H-1,2,4-triazol-3-yl]carbonyl}-N~5~-(diaminomethylidene)-L-ornithyl-L-leucyl-L-isoleucyl-4-fluoro-L-phenylalaninamide (C37 H51 Cl F N11 O5, 784.3 g/mol), in the MolNFT structures on GenesisL1: bound…

Component
C35
Formula
C37 H51 Cl F N11 O5
Class
ligand
Structures
2
PDB entries
1

Binding sites

C35 in 2 structures; the first of them:

  • 2V22 · REPLACE: A strategy for Iterative Design of Cyclin Binding Groove Inhibitors · C35 B1433 · binds MET210, ILE213, LEU214, TRP217, GLU220, VAL221, GLU224, ARG250 and 6 more
  • 2V22 · Replace: a strategy for iterative design of cyclin binding groove inhibitors · C35 B1433 · binds MET210, ILE213, LEU214, TRP217, GLU220, VAL221, GLU224, ARG250 and 6 more

Residues it binds most

GLU 4, ILE 4, LEU 4, THR 4, ARG 4, ASP 4, GLN 4, MET 4, TRP 4, VAL 2 (residue and the binding sites it lines).

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