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Ligand · C2M

C2M · 5-(3,4-dichlorophenyl)-6-methylpyrimidine-2,4-diamine

C2M, 5-(3,4-dichlorophenyl)-6-methylpyrimidine-2,4-diamine (C11 H10 Cl2 N4, 269.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
C2M
Formula
C11 H10 Cl2 N4
Class
ligand
Structures
2
PDB entries
1

Binding sites

C2M in 2 structures; the first of them:

  • 2AOV · Histamine Methyltransferase Complexed with the Antifolate Drug Metoprine · C2M A401 · binds TYR15, PHE19, PHE22, GLU28, GLN143, TYR146, TYR147, VAL173 and 6 more
  • 2AOV · Histamine methyltransferase complexed with the antifolate drug metoprine · C2M A401 · binds TYR15, PHE19, PHE22, GLU28, GLN143, TYR146, TYR147, VAL173 and 6 more

Residues it binds most

TYR 4, PHE 4, GLN 4, GLU 4, TRP 4, VAL 4, CYS 2 (residue and the binding sites it lines).

Found with

  • 4DI · 4-(dimethylamino)butyl imidothiocarbamate

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