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Ligand · C19

C19 · 3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one

C19, 3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one (C24 H23 N5 O, 397.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
C19
Formula
C24 H23 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

C19 in 2 structures; the first of them:

  • 3CP9 · Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor · C19 A501 · binds LEU840, VAL848, ALA866, VAL867, LYS868, GLU885, ILE888, LEU889 and 16 more
  • 3CP9 · Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor · C19 A501 · binds LEU840, VAL848, ALA866, VAL867, LYS868, GLU885, ILE888, LEU889 and 16 more

Residues it binds most

VAL 4, LEU 4, CYS 4, ILE 4, GLU 4, PHE 4, ALA 4, ASP 4, HIS 4, LYS 4 (residue and the binding sites it lines).

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