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Ligand · BWD

BWD · 2-amino-3-(5-bromo-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-propionic acid

BWD, 2-amino-3-(5-bromo-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-propionic acid (C7 H8 Br N3 O4, 278.1 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å…

Component
BWD
Formula
C7 H8 Br N3 O4
Class
ligand
Structures
6
PDB entries
3

Binding sites

BWD in 6 structures; the first of them:

  • 1MQH · Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with… · BWD A301 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, SER140 and 8 more
  • 1MXU · CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) in complex with… · BWD A300 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 8 more
  • 1MY3 · crystal structure of glutamate receptor ligand-binding core in complex with… · BWD A800 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 7 more
  • 1MQH · Crystal structure of the GLUR2 ligand binding core (S1S2J) in complex with… · BWD A301 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, SER140 and 8 more
  • 1MXU · Crystal structure of the GLUR2 ligand binding core (S1S2J) in complex with… · BWD A300 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 8 more
  • 1MY3 · Crystal structure of glutamate receptor ligand-binding core in complex with… · BWD A800 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 7 more

Residues it binds most

LEU 14, THR 14, GLU 14, TYR 14, SER 14, ARG 14, GLY 14, MET 14, PRO 14 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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