GL1X · GenesisL1 explorer

Ligand · BUK

BUK · N~2~-({[(1R)-1-(4-bromophenyl)ethyl]amino}carbonyl)asparaginyl-N~1~-{4-{[amino(imino)methyl]amino}-1-[2,3-dihydro-1,3-thiazol-2-yl(hydroxy)methyl]butyl}valinamide

BUK, N~2~-({[(1R)-1-(4-bromophenyl)ethyl]amino}carbonyl)asparaginyl-N~1~-{4-{[amino(imino)methyl]amino}-1-[2,3-dihydro-1,3-thiazol-2-yl(hydroxy)methyl]butyl}valinamide (C27 H42 Br N9 O5 S, 684.6 g/mol), in the MolNFT structures on…

Component
BUK
Formula
C27 H42 Br N9 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

BUK in 2 structures; the first of them:

  • 1ZPZ · Factor XI catalytic domain complexed with N-((R)-1-(4-bromophenyl)ethyl)urea-Asn-Val-Arg-a… · BUK A900 · binds HIS57, ALA97, GLU98, HIS174, ASP189, ALA190, CYS191, LYS192 and 12 more
  • 1ZPZ · Factor XI catalytic domain complexed with N-((R)-1-(4-bromophenyl)… · BUK A900 · binds HIS57, ALA97, GLU98, HIS174, ASP189, ALA190, CYS191, LYS192 and 12 more

Residues it binds most

GLY 2, ALA 2, ASP 2, CYS 2, GLU 2, HIS 2, SER 2, LYS 2, THR 2, TRP 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.