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Ligand · BMU

BMU · 1-(5-tert-butyl-2-methyl-2H-pyrazol-3-yl)-3-(4-chloro-phenyl)-urea

BMU, 1-(5-tert-butyl-2-methyl-2H-pyrazol-3-yl)-3-(4-chloro-phenyl)-urea (C15 H19 Cl N4 O, 306.8 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
BMU
Formula
C15 H19 Cl N4 O
Class
ligand
Structures
12
PDB entries
6

Binding sites

BMU in 12 structures; the first of them:

  • 1KV1 · p38 MAP Kinase in Complex with Inhibitor 1 · BMU A391 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, VAL83 and 10 more
  • 3O8P · Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor… · BMU A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, VAL83 and 10 more
  • 3O8T · Conformational plasticity of p38 MAP kinase DFG-motif mutants in response to inhibitor… · BMU A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, VAL83 and 10 more
  • 3O8U · Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor… · BMU A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, VAL83 and 10 more
  • 3OBJ · Conformational plasticity of p38 MAP kinase DFG mutants in response to inhibitor binding · BMU A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, VAL83 and 10 more
  • 3OC1 · Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor… · BMU A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, ILE84 and 7 more
  • 1KV1 · P38 MAP kinase in complex with inhibitor 1 · BMU A391 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, VAL83 and 10 more
  • 3O8P · Conformational plasticity of P38 MAP kinase dfg motif mutants in response to inhibitor… · BMU A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, VAL83 and 10 more
  • 3O8T · Conformational plasticity of P38 MAP kinase dfg-motif mutants in response to inhibitor… · BMU A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, VAL83 and 10 more
  • 3O8U · Conformational plasticity of P38 MAP kinase dfg motif mutants in response to inhibitor… · BMU A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, VAL83 and 10 more
  • 3OBJ · Conformational plasticity of P38 MAP kinase dfg mutants in response to inhibitor binding · BMU A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, VAL83 and 10 more
  • 3OC1 · Conformational plasticity of P38 MAP kinase dfg motif mutants in response to inhibitor… · BMU A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, MET78, ILE84 and 7 more

Residues it binds most

LEU 12, ILE 12, VAL 12, ALA 12, GLU 12, HIS 12, LYS 12, MET 12, THR 12, ASP 10 (residue and the binding sites it lines).

Found with

  • BOG · octyl beta-D-glucopyranoside
  • EDO · 1,2-ethanediol

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