Ligand · BFF

BFF · 3-[(4-bromo-2,6-difluorobenzyl)oxy]-5-{[(4-pyrrolidin-1-ylbutyl)carbamoyl]amino}isothiazole-4-carboxamide

BFF, 3-[(4-bromo-2,6-difluorobenzyl)oxy]-5-{[(4-pyrrolidin-1-ylbutyl)carbamoyl]amino}isothiazole-4-carboxamide (C20 H24 Br F2 N5 O3 S, 532.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component: BFF
Formula: C20 H24 Br F2 N5 O3 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

BFF in 2 structures; the first of them:

3L8S · Human p38 MAP Kinase in Complex with CP-547632 · BFF A361 · binds VAL30, VAL38, ALA51, VAL52, LYS53, LEU75, ILE84, LEU86 and 13 more
3L8S · Human P38 MAP kinase in complex with cp-547632 · BFF A361 · binds VAL30, VAL38, ALA51, VAL52, LYS53, LEU75, ILE84, LEU86 and 13 more

Residues it binds most

LEU 2, VAL 2, ALA 2, ASN 2, ASP 2, GLY 2, HIS 2, ILE 2, LYS 2, MET 2 (residue and the binding sites it lines).

Found with

BOG · octyl beta-D-glucopyranoside

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