Ligand · B7R

B7R · 4-[(1-methylcyclopropyl)amino]-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]-6-pyrimidin-5-yl-pyrido[4,3-d]pyrimidin-5-one

B7R, 4-[(1-methylcyclopropyl)amino]-2-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]-6-pyrimidin-5-yl-pyrido[4,3-d]pyrimidin-5-one (C24 H28 N10 O, 472.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component: B7R
Formula: C24 H28 N10 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

B7R in 2 structures; the first of them:

7QG5 · IRAK4 in complex with inhibitor · B7R A501 · binds MET192, GLY193, GLU194, VAL200, ALA211, LYS213, GLU233, VAL246 and 15 more
7QG5 · IRAK4 in complex with inhibitor · B7R A501 · binds MET192, GLY193, GLU194, VAL200, ALA211, LYS213, GLU233, VAL246 and 15 more

Residues it binds most

ASP 4, VAL 4, GLU 4, GLY 4, MET 4, SER 4, TYR 4, ALA 4, ARG 4, ASN 4 (residue and the binding sites it lines).

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