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Ligand · B5Z

B5Z · ~{N}-[5-[3-(2-morpholin-4-ylethylcarbamoylamino) phenyl]-[1,3]thiazolo[5,4-b]pyridin-2-yl]cyclopropanecarboxamide

B5Z, ~{N}-[5-[3-(2-morpholin-4-ylethylcarbamoylamino) phenyl]-[1,3]thiazolo[5,4-b]pyridin-2-yl]cyclopropanecarboxamide (C23 H26 N6 O3 S, 466.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
B5Z
Formula
C23 H26 N6 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

B5Z in 2 structures; the first of them:

  • 6EIJ · DYRK1A in complex with HG-8-60-1 · B5Z A501 · binds ILE165, PHE170, ALA186, LYS188, PHE238, GLU239, MET240, LEU241 and 5 more
  • 6EIJ · DYRK1A in complex with hg-8-60-1 · B5Z A501 · binds ILE165, PHE170, ALA186, LYS188, PHE238, GLU239, MET240, LEU241 and 5 more

Residues it binds most

LEU 8, PHE 8, SER 8, GLU 8, LYS 8, ALA 8, ASP 8, MET 8, VAL 8, ILE 6 (residue and the binding sites it lines).

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