Ligand · AZ5

AZ5 · 5-chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine

AZ5, 5-chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (C14 H14 Cl F N8, 348.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component: AZ5
Formula: C14 H14 Cl F N8
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

AZ5 in 2 structures; the first of them:

2XA4 · Inhibitors of Jak2 Kinase domain · AZ5 A2131 · binds LEU855, GLY856, LYS857, VAL863, ALA880, VAL911, MET929, GLU930 and 12 more
2XA4 · Inhibitors of JAK2 kinase domain · AZ5 A2131 · binds LEU855, GLY856, LYS857, VAL863, ALA880, VAL911, MET929, GLU930 and 12 more

Residues it binds most

GLY 4, LEU 4, TYR 4, VAL 4, ALA 4, ARG 4, ASN 4, ASP 4, GLU 4, ILE 4 (residue and the binding sites it lines).

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