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Ligand · AZ2

AZ2 · (2S)-2-ethoxy-3-[4-(2-{4-[(methylsulfonyl)oxy]phenyl}ethoxy)phenyl]propanoic acid

AZ2, (2S)-2-ethoxy-3-[4-(2-{4-[(methylsulfonyl)oxy]phenyl}ethoxy)phenyl]propanoic acid (C20 H24 O7 S, 408.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5…

Component
AZ2
Formula
C20 H24 O7 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

AZ2 in 4 structures; the first of them:

  • 1I7G · Crystal structure of the ligand binding domain from human ppar-alpha in complex with the… · AZ2 A469 · binds ILE241, LEU247, GLU251, ILE272, PHE273, CYS275, CYS276, GLN277 and 15 more
  • 1I7I · Crystal structure of the ligand binding domain of human ppar-gamma in complex with the… · AZ2 A101 · binds ARG280, ILE281, PHE282, GLY284, CYS285, GLN286, ARG288, SER289 and 13 more
  • 1I7G · Crystal structure of the ligand binding domain from human ppar-alpha in complex with the… · AZ2 A469 · binds ILE241, LEU247, GLU251, ILE272, PHE273, CYS275, CYS276, GLN277 and 15 more
  • 1I7I · Crystal structure of the ligand binding domain of human ppar-gamma in complex with the… · AZ2 A101 · binds ARG280, ILE281, PHE282, GLY284, CYS285, GLN286, ARG288, SER289 and 13 more

Residues it binds most

ILE 6, LEU 6, PHE 6, HIS 6, MET 6, TYR 6, ARG 4, CYS 6, VAL 6, GLN 6 (residue and the binding sites it lines).

Found with

  • CPQ · N,N-bis(3-D-gluconamidopropyl)deoxycholamide
  • NA · Sodium ion

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