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Ligand · AWU

AWU · [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene) pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate

AWU, [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene) pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate (C15 H24 N2…

Component
AWU
Formula
C15 H24 N2 O16 P2
Class
ligand
Structures
5
PDB entries
3

Binding sites

AWU in 5 structures; the first of them:

  • 6IJA · Crystal Structure of Arabidopsis thaliana UGT89C1 complexed with UDP-L-rhamnose · AWU A900 · binds GLN18, SER19, GLY20, HIS21, VAL23, LEU88, ILE148, GLY249 and 13 more
  • 7JID · Crystal structure of the L780 UDP-rhamnose synthase from Acanthamoeba polyphaga mimivirus · AWU A301 · binds THR59, THR66, ILE67, THR106, CYS108, TYR136, ILE159, ARG160 and 15 more
  • 8TWS · AvrB bound with UDP-rhamnose and RIN4 C-NOI motif · AWU A1001 · binds GLY46, ALA47, ALA48, ASN62, TYR65, CYS66, ARG99, PHE113 and 12 more
  • 6IJA · Crystal structure of arabidopsis thaliana UGT89C1 complexed with udp- L-rhamnose · AWU A900 · binds GLN18, SER19, GLY20, HIS21, VAL23, LEU88, ILE148, GLY249 and 13 more
  • 7JID · Crystal structure of the L780 udp-rhamnose synthase from acanthamoeba polyphaga mimivirus · AWU A301 · binds THR59, THR66, ILE67, THR106, CYS108, TYR136, ARG160, MET161 and 11 more

Residues it binds most

GLY 5, ILE 8, GLN 8, ARG 5, THR 5, HIS 9, SER 5, ALA 5, TYR 5, CYS 5 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • EDO · 1,2-ethanediol

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