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Ligand · AW0

AW0 · 5'-deoxy-5'-[(3-{[(4-methylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]adenosine

AW0, 5'-deoxy-5'-[(3-{[(4-methylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]adenosine (C24 H34 N8 O4, 498.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
AW0
Formula
C24 H34 N8 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

AW0 in 2 structures; the first of them:

  • 4EQZ · Crystal structure of human DOT1L in complex with inhibitor FED2 · AW0 A501 · binds TYR128, PRO130, PHE131, PRO133, GLU134, SER140, VAL144, ASP161 and 22 more
  • 4EQZ · Crystal structure of human DOT1L in complex with inhibitor FED2 · AW0 A501 · binds TYR128, PRO130, PHE131, PRO133, GLU134, SER140, VAL144, ASP161 and 22 more

Residues it binds most

VAL 2, PHE 2, SER 2, GLY 2, PRO 2, ASP 2, GLU 2, TYR 2, ALA 2, ASN 2 (residue and the binding sites it lines).

Found with

  • UNX · Unknown atom or ion

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