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Ligand · AV3

AV3 · 4-[(4-fluoro-2-methyl-3H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline

AV3, 4-[(4-fluoro-2-methyl-3H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline (C25 H27 F N4 O3, 450.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
AV3
Formula
C25 H27 F N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

AV3 in 2 structures; the first of them:

  • 6IW7 · structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib… · AV3 B301 · binds GLY94, MET95, HIS117, ARG119, TRP174, SER70, ILE71, SER72 and 4 more
  • 6IW7 · Structural insights into mycobacterium tuberculosis CLPP1P2 inhibition by cediranib… · AV3 B301 · binds GLY94, MET95, HIS117, ARG119, TRP174, SER70, ILE71, SER72 and 3 more

Residues it binds most

ILE 14, SER 14, MET 14, ARG 14, GLU 14, GLY 14, HIS 14, TRP 14, S0R 7, GLN 2 (residue and the binding sites it lines).

Found with

  • BEZ · Benzoic acid

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