Ligand · ARZ
ARZ · (3S,5S,7S)-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl) tricyclo[3.3.1.1~3,7~]decane-1-carboxamide
ARZ, (3S,5S,7S)-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl) tricyclo[3.3.1.1~3,7~]decane-1-carboxamide (C13 H18 N4 O3 S2, 342.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…
- Component
- ARZ
- Formula
- C13 H18 N4 O3 S2
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
ARZ in 4 structures; the first of them:
- 3MHC · Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of… · ARZ A263 · binds ASN67, ILE91, GLN92, HIS94, HIS96, GLU106, HIS119, VAL121 and 7 more
- 7JOC · Carbonic Anhydrase IX Mimic Complexed with N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)adamantane… · ARZ A302 · binds LEU91, GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, VAL131 and 7 more
- 3MHC · Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of… · ARZ A263 · binds ASN67, ILE91, GLN92, HIS94, HIS96, GLU106, HIS119, VAL121 and 7 more
- 7JOC · Carbonic anhydrase IX mimic complexed with N-(5-sulfamoyl-1,3,4… · ARZ A302 · binds LEU91, GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, VAL131 and 7 more
Residues it binds most
HIS 4, VAL 4, THR 4, LEU 4, GLN 4, GLU 4, SER 4, TRP 4, ASN 2, ILE 2 (residue and the binding sites it lines).
Found with
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