Ligand · AQB

AQB · N-(4-{[4-({[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]carbamoyl}amino)phenyl]amino}quinazolin-6-yl)-4-(dimethylamino)butanamide

AQB, N-(4-{[4-({[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]carbamoyl}amino)phenyl]amino}quinazolin-6-yl)-4-(dimethylamino)butanamide (C34 H40 N10 O2, 620.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component: AQB
Formula: C34 H40 N10 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

AQB in 2 structures; the first of them:

3TZ7 · Kinase domain of cSrc in complex with RL103 · AQB A601 · binds LEU273, VAL281, ALA293, LYS295, GLU310, VAL313, MET314, LEU317 and 15 more
3TZ7 · Kinase domain of csrc in complex with RL103 · AQB A601 · binds LEU273, VAL281, ALA293, LYS295, GLU310, VAL313, MET314, LEU317 and 15 more

Residues it binds most

LEU 4, VAL 4, ALA 4, ASP 4, GLU 4, MET 4, GLY 4, TYR 4, HIS 4, LYS 4 (residue and the binding sites it lines).

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