Ligand · APJ
APJ · N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine
APJ, N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine (C17 H16 N8, 332.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5…
- Component
- APJ
- Formula
- C17 H16 N8
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
APJ in 4 structures; the first of them:
- 3FBV · Crystal structure of the oligomer formed by the kinase-ribonuclease domain of Ire1 · APJ A1999 · binds LEU680, GLY681, TYR682, VAL689, ALA700, LYS702, LEU745, GLU746 and 10 more
- 3SDJ · Structure of RNase-inactive point mutant of oligomeric kinase/RNase Ire1 · APJ A1999 · binds LEU680, GLY681, TYR682, VAL689, ALA700, LYS702, LEU745, GLU746 and 9 more
- 3FBV · Crystal structure of the oligomer formed by the kinase-ribonuclease domain of IRE1 · APJ A1999 · binds LEU680, GLY681, TYR682, VAL689, ALA700, LYS702, LEU745, GLU746 and 10 more
Residues it binds most
LEU 56, ASP 56, ASN 56, ALA 56, CYS 56, GLN 56, GLU 56, GLY 56, LYS 56, SER 56 (residue and the binding sites it lines).
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.