Ligand · AM8

AM8 · N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide

AM8, N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide (C23 H22 Cl N3 O3 S, 456.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component: AM8
Formula: C23 H22 Cl N3 O3 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

AM8 in 2 structures; the first of them:

2RFS · X-ray structure of SU11274 bound to c-Met · AM8 A1 · binds ILE1084, GLY1085, VAL1092, ALA1108, LEU1140, LEU1157, PRO1158, TYR1159 and 11 more
2RFS · X-ray structure of SU11274 bound to C-met · AM8 A1 · binds ILE1084, GLY1085, VAL1092, ALA1108, LEU1140, LEU1157, PRO1158, TYR1159 and 11 more

Residues it binds most

ALA 2, ASP 2, GLY 2, LEU 2, MET 2, TYR 2, ARG 2, ASN 2, ILE 2, LYS 2 (residue and the binding sites it lines).

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