Ligand · AM7

AM7 · 2-benzyl-5-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-3-methylpyrimidin-4(3H)-one

AM7, 2-benzyl-5-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-3-methylpyrimidin-4(3H)-one (C35 H35 F N4 O5, 610.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component: AM7
Formula: C35 H35 F N4 O5
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

AM7 in 2 structures; the first of them:

2RFN · x-ray structure of c-Met with inhibitor. · AM7 A1 · binds ILE1084, PHE1089, VAL1092, ALA1108, LYS1110, LEU1112, PHE1124, GLU1127 and 15 more
2RFN · X-ray structure of C-met with inhibitor. · AM7 A1 · binds ILE1084, PHE1089, VAL1092, ALA1108, LYS1110, LEU1112, PHE1124, GLU1127 and 15 more

Residues it binds most

LEU 4, MET 4, ALA 4, GLY 4, ILE 4, LYS 4, PHE 4, VAL 4, ASP 2, GLU 4 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.