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Ligand · AM1

AM1 · (S)-2-amino-3-(3-carboxy-5-methylisoxazol-4-yl)propionic acid

AM1, (S)-2-amino-3-(3-carboxy-5-methylisoxazol-4-yl)propionic acid (C8 H10 N2 O5, 214.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
AM1
Formula
C8 H10 N2 O5
Class
ligand
Structures
4
PDB entries
2

Binding sites

AM1 in 4 structures; the first of them:

  • 1M5E · X-ray structure of the GLUR2 ligand binding core (S1S2J) in complex with acpa at 1.46 a… · AM1 A1700 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, THR137, LEU138 and 9 more
  • 1M5F · X-ray structure of the GLUR2 ligand binding core (S1S2J-Y702F) in complex with acpa at… · AM1 A1200 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, SER140 and 9 more
  • 1M5E · X-ray structure of the GLUR2 ligand binding core (S1S2J) in complex with acpa at 1.46 a… · AM1 A1700 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, THR137, LEU138 and 9 more
  • 1M5F · X-ray structure of the GLUR2 ligand binding core (S1S2J-Y702F) in complex with acpa at… · AM1 A1200 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, SER140 and 9 more

Residues it binds most

LEU 12, THR 12, GLU 12, SER 12, TYR 12, ARG 12, GLY 12, MET 12, PRO 12 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • ACT · Acetate ion

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