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Ligand · AFP

AFP · 1,6-di-O-phosphono-alpha-D-fructofuranose

AFP, 1,6-di-O-phosphono-alpha-D-fructofuranose (C6 H14 O12 P2, 340.1 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
AFP
Formula
C6 H14 O12 P2
Class
sugar
Structures
4
PDB entries
2

Binding sites

AFP in 4 structures; the first of them:

  • 1FBH · Crystallographic studies of the catalytic mechanism of the neutral form of… · AFP A336 · binds ASP121, GLY122, SER123, SER124, ASN212, TYR215, TYR244, GLY246 and 9 more
  • 1LLC · Structure determination of the allosteric L-lactate dehydrogenase from lactobacillus… · AFP A1 · binds THR169, ALA170, ARG173, ARG185, VAL187, HIS188, ALA189, TYR190 and 4 more
  • 1FBH · Crystallographic studies of the catalytic mechanism of the neutral form of… · AFP A336 · binds ASP121, GLY122, SER123, SER124, ASN212, TYR215, TYR244, GLY246 and 9 more
  • 1LLC · Structure determination of the allosteric L-lactate dehydrogenase from lactobacillus… · AFP A1 · binds THR169, ALA170, ARG173, ARG185, VAL187, HIS188, ALA189, TYR190 and 4 more

Residues it binds most

ARG 6, TYR 6, SER 4, GLY 4, LEU 6, ALA 2, ASN 4, ASP 4, LYS 4, MET 4 (residue and the binding sites it lines).

Found with

  • FBP · 1,6-di-O-phosphono-beta-D-fructofuranose
  • SO4 · Sulfate ion

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